Question 8. 
 
A 52-year-old woman presented with hot flushes. Her last menstrual period had been 1 year 
previously. She was treated with ethinylestradiol and medroxyprogesterone acetate. 
 
Which potential consequence of oestrogen therapy is most reduced by co-prescription of a 
progestogen? 
 
A breast cancer 
B breast pain 
C endometrial cancer 
D mood changes 
E weight gain