Study Set Content:
contains fenestrations. has a shield of negativity which repels negatively charged molecules
capillary endothelium
allows further restriction of larger molecules. sandwiched between podocytes and capillary endothelium
basement membrane
specialized cells that have extending processes that adhere to the basement membrane. filters blood and creates ultrafiltrate (filtration slits)
podocyte epithelium
how much is being filtered by the kidney every 1200-1500 mL of blood being received?
125-130mL
the amount of blood being filtered per minute
glomerular filtration rate
directly related to the number of functioning nephrons
glomerular capillary filtration coefficient
net filtration pressure
determinants of glomerular filtration rate
types of fire extinguisher
occurs when substances move from the tubular lumen to the peritubular capillary plasma
tubular reabsorption
movement of substances from the peritubular capillary plasma to the tubular lumen. tubular cells secrete products of their own cellular metabolism into the filtrate in the tubular lumen.
tubular secretion
structures involved in tubular reabsorption and secretion
proximal convoluted tubule, loops of Henle and distal convoluted tubule
requires the presence of transport CHONS and the expenditure of energy to transpory substances across the membrane
active transport
plasma concentration of substance at which active transport stops, and the substance starts to appear in the urine
renal threshold
renal threshold of glucose
160-180 mg/dL
no expenditure of energy transport substances across the membrane. it includes simple diffusion (osmosis) and facilitated diffusion
passive transport
is the diffusion of water from an area of higher water concentration to an area of low water concentration
osmosis
diffusion across the gradient is facilitated by transport CHONs
facilitated diffusion
Loop of Henle two segments
descending segment and ascending segment
impermeable to water. it actively reabsorb salts and other inorganic ions
ascending segment
