Observational
Case Control/
Cohort/
Retrospective
Presence of cases or absence of controls of a disease
Case Control/
Cohort/
Retrospective
Presence or absence of risk factors
Cohort/ Prospective
Inexpensive
Case Control/
Retrospective
Less recall bias
Cohort/Prospective
Recall bias
Case control/Retrospective
Time consuming, expensive
Cohort/Prospective
Retrospective
Case control
Prospective
Cohort
Experimental (GOLD STANDARD)
Randomized Controlled Clinical Trial
Survey
Cross-Sectional/ Prevalence
Disease prevalence and prevalence factors
Cross-sectional/ Prevalence studies
Compares 2 or more treatment and placebo
RCT
Decreased bias and confounding
Randomized Controlled Clinical Trials
Blinded or double blinded
RCT
Costly and time-
intensive, ethical
considerations
RCT
Have the capacity to cause
error
A
Increased patient monitoring
D
Did not reach the patient
B
Reached the patient
C