Basic Immunology Final; practice questions
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MCB 4211,
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Page 7 of 8
then lymph node cells from those treated animals were cultured in the presence of collagen (black bars)
or the lectin PHA (grey bars) or with no added stimulant (open bars). Why is the PHA response greater
than the collagen response in both treatment groups?
a.
there are more cells that will proliferate in the
presence of a polyclonal activator than are
specifically responsive to collagen
b.
PHA is an agglutinin and thus clumps and kills
the cells
c.
the collagen is an extracellular matrix proteins
and stimulates cells to adhere
d.
PHA is a better activator because it provides
nutrients for the cells
e.
all of the above are true
35.
What is the difference between a TSTA, tumor specific transplantation antigen and a TATA, tumor
associated transplantation antigen?
a.
both are expressed on T cells, but only TSTA are expressed on B cells
b.
only TSTAs are viral antigens
c.
some TATAs are also found on embryos or fetal tissues
d.
all of the above are true
e.
none of the above are true
36.
What kinds of genes are important in tumorigenesis?
a.
kinases
b.
phosphatases
c.
telomerases
d.
transcription factors
e.
all of the above
37.
Why is AIDS now treated simultaneously with multiple different antagonists of the HIV life cycle?
a.
the HIV polymerase is error prone, making a simple single target approach susceptible to
breakout mutants that are resistant to the therapy
b.
each drug targets a different serotype of HIV
c.
the dose makes the poison, so using multiple drugs means that each drug can be used at a lower
dose.
d.
all of the above are true
e.
none of the above are true
38.
What is the Hayflick limit?
a.
the number of T cells that are normally present in a healthy person
b.
the number of cell divisions that a cell normally can undergo before senescence
c.
the number of complement genes that are active
d.
the number of genes that must be mutant to make a cancerous phenotype
e.
the distance a cell can chemotax