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         a) Increased
         b) Decreased
         c) Not changed
5.7) 400 mg of a drug is administered to a patient and the drug is later measured in
plasma to be 1 µg/ml. What is the apparent volume of distribution (Vd)?
         a) 0.04 L
         b) 0.4 L
         c) 4 L
         d) 40 L
         e) 400 L
5.8) Elderly patients often have ____ muscle mass and thus a(n) ____ Vd.
         a) More; Increased
         b) More; Decreased
         c) Less; Increased
         d) Less; Decreased
5.9) Patients with ascites or edema would have ____ Vd for hydrophilic drugs, such as
gentamicin.
a) Increased
b) Decreased
c) Unchanged

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