Pharmacrystal

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3

50% R, what is the potency compared with a 100% R enantiomer solution?
       a) 4 * R + 1 * S = 1
       b) 4 * R + 1 * S = 1.5
       c) 4 * R + 1 * S = 2
       d) 4 * R + 1 * S = 2.5
       e) 4 * R + 1 * S = 4
2.8) What determines the degree of movement of a drug between body compartments?
       a) Partition constant
       b) Degree of ionization
       c) pH
       d) Size
       e) All of the above
3.1) Which of the following is NOT a protein target for drug binding?
       a) Side of action (transport)
       b) Enzymes
       c) Carrier molecules
       d) Receptors
       e) Ion channels
3.2) Which of the following is an example of a drug acting directly through receptors?
       a) Protamine binds stoichiometrically to heparin anticoagulants
       b) Adrenergic beta blockers for thyroid hormone-induced tachycardia
       c) Epinephrine for increasing heart rate and blood pressure
       d) Cancer chemotherapeutic agents
       e) Mannitol for subarachnoid hemmorhage
4.1) What is added with drug subclassification, such as an antitubercular drug versus an
antibacterial drug?
       a) Cost
       b) Size
       c) Ionization
       d) Precision
       e) Speed
4.2) What type of drug is propranolol (Inderal)?
       a) Anticonvulsive
       b) Antihypertensive
       c) Antinauseant
       d) Antihistamine
       e) Antipyretic
5.1) Which of the following is considered the brand name?
       a) Propranolol
       b) Inderal
       c) Adrenergic ß-blocker
       d) “off label” use
       e) Blocks ß-receptors in heart myocardium
5.2) Which of the following is considered the class?
a) Propranolol
         b) Inderal
         c) Adrenergic ß-blocker
         d) “off label” use
         e) Blocks ß-receptors in heart myocardium
5.3) Which of the following cases would be contraindicated for propranolol (Inderal)?
         a) Hypertension
         b) Essential tremor
         c) Angina