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4

         d) Tachycardia
         e) Asthma
5.4) Which of the following adverse effects (side-effects) is NOT commonly seen with
cholinergic antagonists?
         a) Blurred vision
         b) Confusion
         c) Miosis
         d) Constipation
         e) Urinary retention
6.1) The drug chloramphenicol (Chloromycetin) is risky for which of the following?
         a) Neonates
         b) Geriatric patients
         c) Adult males
         d) Obese patients
         e) Congestive heart failure patients
6.2) How does the glomerular filtration rate (GFR) change after the age of 40?
         a) Increase 1% each year
         b) Increases 2% each year
         c) Decreases 1% each year
         d) Decreases 2% each year
         e) Does not depend on age
6.3) A decrease in renal and liver function, as seen in the elderly, would prolong drug
half-life, ____ plasma protein binding, and ____ volume of distribution.
         a) Increase; Increase
         b) Decrease; Decrease
         c) Increase; Decrease
         d) Decrease; Increase
6.4) When prescribing isoniazid (Rimifon), pharmacogenetics must be considered as
>90% of Asians and certain other groups are ____ acetylators, and thus have a ____
blood concentration of a given dose and a decreased risk of toxicity.
         a) Slow; Increased
         b) Slow; Decreased
         c) Fast; Increased
         d) Fast; Decrease
6.5) Which of the following are the two modifying factors that contribute to why women
have higher blood peak concentrations of alcohol than men when consuming equivalent
amounts?
a) Lower blood volume & increased hormones
b) Lower fat content & more gastric alcohol dehydrogenase (ADH)
c) Higher fat content & more gastric alcohol dehydrogenase (ADH)
d) Lower fat content & less gastric alcohol dehydrogenase (ADH)
e) Higher fat content & less gastric alcohol dehydrogenase (ADH)

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