Pharmacrystal

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6

        b) Lipid diffusion
        c) Carrier molecules
        d) Endocytosis and exocytosis
5.3) Which of the following drug permeation mechanisms uses the Henderson-
Hasselbalch equation for the ratio of solubility for the weak acid or weak base?
        a) Aqueous diffusion
        b) Lipid diffusion
        c) Carrier molecules
        d) Endocytosis and exocytosis
5.4) Which of the following drug permeation mechanisms is used for peptides, amino
acids, glucose, and other large or insoluble molecules?
        a) Aqueous diffusion
        b) Lipid diffusion
        c) Carrier molecules
        d) Endocytosis and exocytosis
5.5) Which of the following drug permeation mechanisms uses caveolae?
        a) Aqueous diffusion
        b) Lipid diffusion
        c) Carrier molecules
        d) Endocytosis and exocytosis
6.1) Using the Fick Law of Diffusion, how will flux change if membrane thickness is
doubled?
        a) It will double
        b) It will quadruple
        c) It will halve
        d) It will quarter
        e) It will not change
6.2) Using the Fick Law of Diffusion, how will flux change if the permeability
coefficient is quadrupled?
        a) It will double
        b) It will quadruple
        c) It will halve
        d) It will quarter
        e) It will not change
7.1) Which of the following is the amount of a drug absorbed per the amount
administered?
        a) Bioavailability
        b) Bioequivalence
        c) Drug absorption
        d) Bioinequivalence
        e) Dosage
7.2) Which of the following is NOT needed for drug bioequivalence?
        a) Same active ingredients
        b) Same strength or concentration
        c) Same dosage form
        d) Same route of administration
        e) Same side effects
7.3) For intravenous (IV) dosages, what is the bioavailability assumed to be?
        a) 0%
        b) 25%
        c) 50%
        d) 75%
        e) 100%