Study Set Content:
a further problem with these molecules is that when they are in (blank) they are not readily extracted away from excipients, since they are quite (blank) in organic solvents which are immiscible with water.
suspensions, insoluble
Using the formation of a complex with the (blank) in the presence of (blank) as a catalyst, a derivative of the penicillin structure
mercuric ion, imidazole
Using the formation of a complex with the mercuric ion in the presence of imidazole as a catalyst, a derivative of the penicillin structure is produced, which has an absorption maximum between
325 and 345 nm.
. In the assay, comparison with (blank) for the particular penicillin is carried out rather than relying on a standard A (1%, 1 cm) value.
pure standard
This assay is used by the BP fbr analysis of preparations containing
ampicillin, amoxicillin, carbenicillin, cloxacillin, flucloxacillin and phenoxymethylpenicillin
. The assay is not used for the closely related
cefalexins
Assay of adrenaline in lidocaine (lignocaine) adrenaline injection
is present as a vasoconstrictor in some local anaesthetic injections in a much smaller amount than the local anaesthetic itself
Adrenaline
Adrenaline is present as a vasoconstrictor in some local anaesthetic injections in a much smaller amount than the local anaesthetic itself, which obscures the (blank) of adrenaline in the UV region.
absorption
The selectivity of UV/visible spectroscopy for the analysis of adrenaline can be increased by complex formation, which occurs between (blank) and molecules containing a (blank)
iron (II), catechol group
These complexes are purple in colour and absorb at ca
540 nm,
The adrenaline in the injection is quantified against a (blank) of adrenaline
standard solution
