Study Set Content:
Maintains the precise lipid pattern that is critical in normal survival of RBC in circulation
Aminophospholipid
Is a negative receptor
Phosphatidylserine
contributes to signaling of splenic macrophages ending up in phagocytosis of the aged RBC and resulting to extravascular hemolysis.
Phosphatidylserine
Is in equal proportion on both sides of the lipid bilayer and affects the surface area of the cell and membrane permeability.
Cholesterol
cholesterol is partially converted into an esterified by the action of:
lecithin-cholesterol acyltransferase (LCAT)
Where is Lecithin-cholesterol acyltransferase synthesized?
Liver
Abnormally shaped Cell
Poikilocyte
Expanding of the outer leaflet will result in spiky appearance forming the?
Echinocytes
What appearance does the echinocyte have?
Sea-urchin appearance
Expanding of the inner leaflet will result in stomatocytosis forming?
Stomatocytes
Appearance of Stomatocytes
Kiss lips or coffee bean shaped
The show relationship includes:
Horizontal and Vertical Interaction
Brings skeletal support in the membrane lipid bilayer
Horizontal Interaction
It makes the membrane stable, because peripheral proteins are connected and stabilized to the integral protein
Vertical Interaction
What would happen if RBCs are free floating?
It will increase in size
What would to the RBCs happen if the proteins detach?
RBCs will wiggle
What type of protein is glycophorin?
Integral Protein
Principal RBC glycoprotein; Accounts for most of the membrane
sialic acid
Glycophorin
What gives RBCs negative charge?
Sialic acid
What do you call when RBCs repel each other?
Zeta Potential
