Study Set Content:
Chemicals that are normally of low molecular weight and which interact with molecular targets to produce a biological response
Drugs
Drugs are potentially
posions
Biological response may be therapeutically useful in the case o
medicines
Biological response may be therapeutically useful in the case of medicines or harmful in the case of
poison
Classification of Drugs
Acc. To pharmacological effect
. Depending where they act on a particular biochemical process
. Chemical structure
Common feature which is shared by all analgesic
pain killing effect
Act on different target and have no structural
relationship
Ex: antihistamine act by the inhibiting the action of the inflammatory agent (blank) in the body
histamine
share common structural feature and often share a similar pharmacologic activity
Chemical structure
: penicillin contain (blank) and kill bacteria by the same mechanism
β-lactam ring
Why is it when a patient is allergic to penicillin he/she should not be given cephalosporin? Because cephalosporin also contains a
β-lactam ring
Actions of drugs are the (blank) mechanisms by which the chemical produces a response in living organisms.
biochemicals, physiological
The effect is the observable (blank) of drug action
consequence
The biological effects observed after a drug has been administered are the result of(blank) between that chemical and some part of the organism.
interaction
Important target of drug action because almost all biological reactions are carried out under influence of
Enzymes
Drugs may either (blank) or (blank) enzymatic reaction
increase, decrease
Made of protein structure that acts as the body’s catalyst (aids a chemical reaction by lowering the Activation energy of reaction)
Enzyme
Made up of amino acid sub-units linked to together by
Peptide bonds
How many essential amino acids
20
This speed up the rate at which the reactions reaches equilibrium but does not affect the (blank) itself
equilibrium
