Study Set Content:
1- Flashcard

 is the first step which determines the onset of action, absorption, and availability of a drug preparation by all routes of administration (except intravenous) and peroral use of true solutions.


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2- Flashcard

For oral dosage forms such as Tablets and capsules,(blank)is achieved if the active ingredient will be released from its dosage form by disintegration process


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3- Flashcard

Tablets or capsules taken (blank) remain one of the most effective means of treatment available.


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4- Flashcard

The effectiveness of such dosage forms relies on the drug dissolving in the fluids of the gastrointestinal tract prior to absorption into the

systemic circulation.

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The rate of dissolution of the tablet or capsule is therefore


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One of the problems facing the pharmaceutical industry is to optimize the amount of drug available to the body, i.e. its


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7- Flashcard

Inadequacies in bioavailability can mean that the treatment is ineffective and at worst potentially (blank) (toxic overdose)


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8- Flashcard

Control Test for Tablets

1. Organoleptic evaluation

2. Assay for the active ingredient(s)

3. Thickness

4. Hardness/Tensile Strength

5. Friability

6. Uniformity of Dosage Units (Weight Variation or Content Uniformity)

7. Disintegration test

8. Dissolution test

9. ID tests for the active ingredient(s) and possible contaminants

10. Powder fineness/Micromeritics

11. Moisture content

12. Microbiological test

13. Storage condition and stability test

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9- Flashcard

Official Tests:

Weight variation, disintegration, dissolution, drug content

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10- Flashcard

Non-official Test:

: Hardness, Friability, Thickness, Organoleptic Characteristics

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11- Flashcard

Many pharmaceutical tablets use (blank) as a vital means of rapid identification and consumer acceptance


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12- Flashcard

The color of a product must be uniform within a single tablet. Non-uniformity is referred to as (blank) and hence it leads to poor quality of product.


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13- Flashcard

How to distinguish the difference? Eyes Machines like:

• Reflectance spectrophotometry

• Tristimulus colorimetric measurements

• Micro reflectance photometer

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14- Flashcard

The presence of odor in a batch of tablets could indicate stability problems, such as the odor of (blank)in degrading aspirin tablets.

acetic acid

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15- Flashcard

However, the presence of an odor could be characteristics for the drug (blank), added ingredients (blank) or the dosage form (blank).

vitamins, flavoring agents, filmcoated tablet

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16- Flashcard

It is important in consumer acceptance of, especially chewable tablets.


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17- Flashcard

Tablets level of flaws such as:

Chips, cracks, contamination from foreign solid substances, and surface texture

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18- Flashcard

Taste Method of Detection

Visual Inspection Techniques and Electronic Devices

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19- Flashcard

Important in reproducing tablets identical in appearance, but also to ensure that every production lot will be usable with selected packaging components.

Tablet Thickness Test

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20- Flashcard

Also used as counting mechanism using filling equipment.

Tablet Thickness Test

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