Study Set Content:
a mixture of dihydro-a-
ergocryptine and three similar dihydrogenated
peptide ergot alkaloids (ergoloid mesylates), has
been promoted for many years for the relief of
senility and more recently for the treatment of
Alzheimer's dementia.
Dihydroergotoxine,
The most common toxic effects of the ergot
derivatives:
gastrointestinal disturbances,
prolonged vasospasm.
This sign of vascular smooth muscle stimulation
may result in (blank) and may require
amputation.
gangrene
has also been reported and
may require resection.
Bowel infarction
and, in the case of methysergide,
occasional instances of
Drowsiness , central stimulation
and hallucinations.
Consist of the obstructive vascular diseases,
especially symptomatic coronary artery
disease, and
collagen diseases
There is no evidence that ordinary use of
ergotamine for migraine is hazardous in
pregnancy
Use to deliberately caused abortion
is contraindicated because the high dose
required often
dangerous vasoconstriction
Their effects include agonist, partial agonist, and
antagonist actions at a adrenoceptors and
serotonin receptors (especially
5-HT 1A and 5-
HT 1D;
Their effects include agonist, partial agonist, and
antagonist actions at a adrenoceptors and
serotonin receptors (especially 5-HT 1A and 5-
HT 1D; less for
for 5-HT 2 and 5-HT 3
ergot preparations can
evoke rhythmic contraction and relaxation of the
uterus.
very small doses,
