Description

In this collection we will go over the hematologic system, Components of blood, Structures of the Hematologic System, Oncologic Disorders and anemias

This collection is useful for all medical students

Study Set Content:
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Hematologic System, 

Oncologic Disorders & 

Anemias

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Hematology

Study of blood and blood forming tissues

Key components of hematologic system 

are:

Blood

Blood forming tissues

Bone marrow

Spleen

Lymph system

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What Does Blood Do?

Transportation

Oxygen

Nutrients

Hormones

Waste Products

Regulation

Fluid, electrolyte

Acid-Base balance

Protection

Coagulation

Fight Infections

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Components of Blood

Plasma

55%

Blood Cells

45%

Three types

Erythrocytes/RBCs

Leukocytes/WBCs

Thrombocytes/Platelets

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Erythrocytes/Red Blood Cells

Composed of hemoglobin

Erythropoiesis

= RBC production

Stimulated by hypoxia

Controlled by 

erythropoietin

Hormone synthesized in kidney

Hemolysis

= destruction of RBCs

Releases bilirubin into blood stream

Normal lifespan of RBC = 120 days

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Leukocytes/White Blood Cells

5 types

Basophils

Eosinophils

Neutrophils

Monocytes

Lymphocytes

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Types and Functions of Leukocytes

Granulocytes

Neutrophil

Eosinophil

Basophil

Phagocytosis, early phase of 

inflammation
Phagocytosis, parasitic infections
Inflammatory response, allergic 

response

Agranulocytes

Lymphocyte

Monocyte

Cellular, humoral immune response
Phagocytosis; cellular  immune 

response

TYPE

CELL FUNCTION

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Thrombocytes/Platelets

Must be present for clotting to occur

Involved in hemostasis

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Normal Clotting Mechanisms

Hemostasis

Goal: Minimizing blood loss when injured

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Vascular Response

vasoconstriction

2.

Platelet response

Activated during injury

Form clumps (agglutination)

3.

Plasma Clotting Factors

Factors I – XIII

Intrinsic pathway

Extrinsic pathway

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Anticoagulation

Elements that interfere with blood 

clotting

Countermechanism to blood clotting—

keeps blood liquid and able to flow

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Structures of the Hematologic System

Bone Marrow

Liver

Lymph System

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Bone Marrow

Bone Marrow

Soft substance in core of bones

Blood cell production (Hematopoiesis):The 

production of all types of blood cells 

generated by a remarkable self-regulated 

system that is responsive to the demands 

put upon it. 

RBCs

WBCs

Platelets

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