What following conditions are necessary for the RBC to survive for 120 days?
True or False:
If the RBC is immature, it becomes less deformable
False; RBCs become less deformable when they are aged/old/senescent
What removes aged/old/senescent RBCs?
Functions of RBC membrane
RBC Membrane are influenced by:
What makes up surface antigen?
What are the two types of Proteins?
Integral Proteins and Peripheral Proteins
Are membrane proteins that extend from the outer surface and traverse the entire membrane to the inner cytoplasmic site of RBCs:
What proteins are situated right beneath the inner leaflet?
The semi-permeable lipid bilayer is supported by a what:
Give the respective percentage to the following:
CHON (Protein) -
CHON - 52%
Lipids - 40%
CHO - 8%
How many RBC antigens have been identified?
These are present in nearly equimolar quantities
Phospholipids and unesterified cholesterol
What are present in small quantities?
Free fatty acids and Glycolipids
What comprises the External Surface or the outer leaflet?
Hint: You can use the mnemonics, "SPG"
S - Sphingomyelin
P - Phosphatidylcholine
G - Glycolipids
What comprises the Internal Surface or the inner leaflet?
Phospholipids that are situated on the outer leaflet are collectively called
Represents the controlling points in the major pathways of lipid renewal.
Are the gateways in the entry of phospholipids
Phosphatidylcholine & Sphingomyelin
Also known as flippase
Aminophospholipid translocase (ATP-dependent enzyme)