Study Set Content:
quantitative amount administered or taken by a patient for the intended medicinal effect
Dose of a drug
amount taken at one time
single dose
may be subdivided and taken in divided doses, two or more times per day depending on the characteristics of the drug and the illness
Daily dose
amount taken during the course of therapy
total dose
schedule of dosing
dosage regimen
dose of a drug is based on
biochemical and pharmacologic activity, physical and chemical properties, dosage from used, route of administration, various patient factors
dose of a drug for a particular patient may be determined in part on the basis of the patient's?
age, weight, body surface area, general physical health, liver and kidney function, severity of the illness being treated
amount that ordinarily produces the desired therapeutic in the majority of patients in a general or define populations
Usual dose
amount that ordinarily produces the medicinal effect intended in the adult patient
usual adult dose
similarly defined for the infant or child patient
usual pediatric dose
the usual adult and pediatric doses of a drug serves as a?
guide to physician who may select to prescribe that dose initially or vary it depending on the assessed requirements of a particular patient
indicates the quantitative range or amounts of the drug that may be prescribed within the guidelines of usual medicine practice
usual dosage range
the amount that produces the desired intensity of effect in 50% of the individuals tested
median effective dose
amount that produces toxic effects in 50% of the individuals tested
median toxic dose
amount that produces the desired intensity effect in 50% of the individuals tested
median effective dose
amount that produces toxic effects in 50% of individual tested
median toxic dose
An average blood serum concentration of a drug can be measured, and the minimum concentration determined that can be expected to produce the drug's desired effects in a patient.
Minimum effective concentration(MEC)
The base level of blood serum concentrations that produces dose-related toxic effects
Minimum toxic concentration
range of doses that produces therapeutic response without causing any significant adverse effect in patients
Therapeutic window
a ratio between MEC to the MTC
Therapeutic window
