disadvantage of combination products
relative inflexibility in dosing compared with individual drug dosing
advantage of combination products
convenient, enhance compliance, less expensive
example of fixed-dose combination products
amlodopine and benazepril HCL
Whether the fixed-dose combination is a liquid or solid, dosage form when a dose is taken are in
fixed-dose ratio
a number of tablets are scored, or grooved to allow breaking into approximately equal pieces(usually halves)
Splitting tablets
advantages of splitting tablets
dosage flexibility, take a product at a strength that is not otherwise available
They use splitting tablets to
scored or unscored tablets for economic reasons
For some medications, the price of tablets of twice the strength required is similar to lower strenth of tablets
The patient can double his supply by tablet splitting
Solid dosage forms should not be
crushed or cut and must remain intact for proper drug absorption
a variety of measuring devices may be used including calibrated cups, droppers
Dose measurement
For pediatric patients what should be done to ensure accuracy and reducing medication errors.
calibrated oral syringes
House hold spoons vary greatly in capacity
Tablespoons and teaspoons
what can influence the actual volume
viscosity and surface tension of the liquid, technique of the person
what should be only used for the measurement of medication
Calibrated dropper
used as a measure for small volumes of liquid medications
drop(gtt)
delivers approximately how many drops?
20
Drug dosage is determined on the basis of
specific patient parameters
patient's age
– weight
– body surface area
– nutritional and functional status
the range of
dosage determined to be safe and effectve
in that same population group
Usual dosage range
- 1 month to 1 year
Infant
branch of medicine that deals
with disease in children from birth through
adolescence
Pediatrics